There is disagreement about this but the answer is normally no.

The Gail model uses the number of biopsies as a surrogate for the presence of atypical hyperplasia. On the assumption that about 10% of biopsies will show AH, the Gail Model adds 10% of the risk of having AH to the overall risk of the patient for each biopsy. BUT if the biopsy is negative, than there is no reason to add that risk as there is zero risk of AH, not 10% risk of AH (Gail includes a modification to account for this).

If we assume that all AH biopsies will undergo excision, then only enter 1 biopsy with AH. That is, if a core shows AH and an excision is benign, that is only one biopsy.

If the core does not show ADH and no excision is done, do not record a biopsy as there is no AH.

HOWEVER, if the core shows AH and no excision is done, count 1 biopsy with AH. This is because Gail gives a risk to the core and a risk to the AH that when used together calculate the risk of AH.

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